Massachusetts Institute of Technology

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281 Albany Street

The rejuvenated laboratory building at 281 Albany Street is now home to Aileron Therapeutics, a dynamic new company creating novel biopharmaceuticals to aid in the fight against disease.

-71.1029000000 42.3581000000
281 Albany Street

281 Albany Street

281 Albany Street, Cambridge, MA

Status: Complete

Themes: Innovation and collaboration
Renovation and renewal

Completion: 2010

The rejuvenated laboratory building at 281 Albany Street is now home to Aileron Therapeutics, a dynamic new company creating novel biopharmaceuticals to aid in the fight against disease.

Overview

281 Albany Street

Status

Complete

Completion Date

2010

Themes and priorities

Innovation and collaboration
Renovation and renewal

In 2010, MIT transformed a 32,000 square foot property at 281 Albany Street from an obsolete manufacturing plant into a next-generation laboratory facility. In keeping with its history of encouraging collaboration and innovation, the Institute has leased the entire laboratory and office space to Aileron Therapeutics, Inc., a biopharmaceutical company founded in 2005 to develop and advance a revolutionary class of drugs. These drugs, called Stapled Peptides, have demonstrated a unique ability to penetrate cells throughout the body and modulate cell interactions relating to disease. Aileron is building a pipeline of promising new drug candidates, currently targeting cancer, infectious disease, metabolic disease, and immune/inflammatory diseases.

In addition to renovating and upgrading the building’s interior facilities, MIT added windows around the perimeter, relocated the loading dock, and constructed a new accessible entrance. The overall transformation has improved the streetscape along Albany Street and contributed to the area’s appeal for both pedestrians and future research partners.

Image credits

© Steve Dunwell / Esto

Details

Address

281 Albany Street, Cambridge, MA

Renewal Status

Complete

Use

Commercial

Project Team

ArchitectKlingStubbins, Cambridge, MA
Construction manager: The Richmond Group, Hopkinton, MA
MIT team: Ken Williams, MIT Investment Management Company

Scope

32,000 gsf

Map

42.3581000000
-71.1029000000
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